Primary ovarian serous carcinomas with extensive squamous differentiation: a case report and literature review

Abstract Background Primary ovarian serous carcinomas (OSC) with extensive squamous differentiation is a rare, and histological diagnostic criteria biological behavior have not been fully established. We present an extremely rare case of primary OSC the ovary differentiation. Case presentation A 58-year-old (gravidity 3, parity 2) female was admitted complaining abdominal distention for 6 months. No apparent tumor in cervix found by physical examination. Serum levels cancer antigen 125 (CA125) elevated (2723.0 IU/L). Macroscopically, 7 cm left uterine adnexa, 5 right 3 omentum were found. Histological immunochemical tests confirmed diagnosis Debulking surgery resection performed. The patient subsequently received postoperative chemotherapy. Conclusions In summary, inter- intratumor heterogeneity may be reason this phenomenon. established because limited data.